ABSTRACT
Due to a lack of data on various parameters with COVID-19 in the Indian population, this study was carried out to understand the relation among gender, age and comorbidities in Indian population. The data was collected using a questionnaire-based survey form that included questions on demographic characteristics, infection and any pre-underlying conditions (n=1146). The data showed that the male patients had suffered more from COVID-19 (58.6%). Also, the patients suffering from comorbidity are more likely to suffer from a severe form of COVID-19 and obesity/overweight was identified as the most prevalent (n=69) comorbid condition, followed by diabetes (n=35), thyroid (n=19) and hypertension (n=11). In severe COVID-19 cases, 85% of patients had a comorbid condition. In another study of COVID-19 hospitalized-cases, about 97% of patients were found to have an underlying medical condition. Among these, diabetes (55.9%) was identified as the most prevalent comorbidity. Males and older people are at a higher risk of developing COVID-19 infection in Indian population. The comorbid conditions also predisposed individuals to COVID-19 and aggravated the infection. © 2022. ScienceIN.
ABSTRACT
Since the COVID-19 eruption in December 2019, the investigation has been focused on its treatment and preventing the disease spread. Currently, there is no biomarker available that can predict the predisposition and severity of COVID-19 infection. In the present study, we have used the cross-sectional survey study data to decipher the association between the ABO blood group and susceptibility, severity and breakthrough COVID-19 infections. Further, we have also investigated the association between antibody class and the risk of contracting COVID-19 infection. Our results indicated that individuals with blood group B had higher susceptibility to acquire COVID-19 infection. In contrast, blood group A was found to be associated with a low risk of acquiring severe COVID-19. In addition, we did not find any correlation between ABO blood group and breakthrough COVID-19 infections. Further, we examined the association of antibodies;anti-A (blood groups B and O) and anti-B (blood groups A and O) with COVID-19 infection. The analysis of antibody classes showed that anti-A antibody associated with a high predisposition to acquire COVID-19 infection. The present study indicates that blood group B and anti-A antibodies are associated with proneness to COVID-19 infection and severity. © ScienceIN.